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Concentration calculation

Q1: Penicillin V suspension 240 mL (200,000 units/tsp). Sig: 400,000 unit tid.  How many days will this prescription last the patient?

Answer:

1 tsp=4.93 mL

200,000 unit/tsp=200,000 unit/4.93 mL

240 mL=240/4.93=48.68 tsp

48.68 tsp*200,000 unit/tsp=9,736,308.32 unit

9,736,308.32/400,000=24 doses

24/3=8 days

Q2: A prescription calls 1.2 mL of saline as one of its ingredients. A dropper was calibrated and found to deliver 3 mL of saline 10 drops. How many drops is needed to prepare this prescription?

Answer:

Q3: Irinotecan is administered through i.v. infusion at 5 mg/kg in a 21-day cycle. For a patient weighing 70.0 kg, how many mg of irinotecan is required in 3 months?

Answer:

5*70*3=1,050 mg

Q4: In a PK study, A patient took acetaminophen 500 mg. A nurse collected 325 uL of serum from the patient and took 10 uL for dilution to afford a 250 uL solution. The concentration is 4 ug/mL after dilution. What is the concentration in serum?

Answer:

 

Q5: The dose of lucanthone hydrochloride is 5 mg/kg body weight three times a day for 1 week. What should the total daily dose (in grams) be for a patient weighing 120 lb

Answer:

Step 1: Convert lb to kg

Step 2: find out the amount of each dose by multiplying  5 mg/kg*body weight in kg

Step 3: Total dose= 3*7*amount of each dose

Q6: Irinotecan is administered through i.v. infusion at 5 mg/kg in one cycle. For a patient with 165 lb, how many mg of irinotecan is required for 6 cycles

Q7: The dose of drug X is 180 mg/m2, how many milligrams of this drug should be administered to a patients weighing 75 kg with 175 cm height?

Q8: A child weighing 28 lb has a urinary tract infection. The physician ordered the following medication. The pharmacist has on hand streptomycin sulfate injection 1 g/2.5 mL. How many milliliter should be administered every dose?

Rx: Streptomycin sulfate, 20 mg/kg/day

          Sig: q12h, im. Seven days

Q9: A child weighing 80 lb with pneumonia was prescribed Tao 7.5 mg/kg every 6 hours for 5 days? Tao is available only as 250 mg capsules. How many grams will this patients receive per day? How many 250 mg capsules would be needed for this order?

Q10: A child weighing 30 lb needs a drug in a dose of 5 mg/kg. How many milliliters of a pediatric suspension of the drug, containing 20 mg/mL, should the patient receive?

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